UM-SCC-47 cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心

UM-SCC-47 cell line细胞株细胞系 BioVector NTCC质粒载体菌种细胞基因保藏中心
Cell line name UM-SCC-47
Synonyms UMSCC-47; UMSCC47; UM-SCC47; UMSCC047; University of Michigan-Squamous Cell Carcinoma-47
Comments Part of: MD Anderson Cell Lines Project.
Part of: OPC-22 oral and pharyngeal cancer cell line panel.
Characteristics: Contains from 21 to 47 copies of the HPV16 genome.
Doubling time: 2.2 days (PubMed=29156801).
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Omics: Deep exome analysis.
Omics: Deep RNAseq analysis.
Omics: Genome sequenced (low read coverage).
Omics: Protein expression by reverse-phase protein arrays.
Sequence variations Homozygous for NOTCH1 p.Gly192Ter (c.574G>T) (PubMed=31541927).
Has no TP53 mutation (PubMed=12884349).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
STR profile Source(s): Millipore; PubMed=19760794; PubMed=21868764; PubMed=25275298; PubMed=29156801

Markers:
Amelogenin X,Y
CSF1PO 11,13
D3S1358 15
D5S818 11,12
D7S820 11
D8S1179 15
D13S317 8,11
D16S539 8,13
D18S51 18
D21S11 29,30
FGA 23,25
Penta D 9,10
Penta E 12,13
TH01 7,9.3
TPOX 10,11
vWA 18

Publications
PubMed=12884349; DOI=10.1002/hed.10274
Bradford C.R., Zhu S., Ogawa H., Ogawa T., Ubell M., Narayan A., Johnson G., Wolf G.T., Fisher S.G., Carey T.E.
P53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

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