HS944T cell line细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

HS944T cell line细胞株

Cell line name Hs 944.T
Synonyms Hs-944-T; HS-944-T; HS 944T; Hs944T; HS944T; HS 944; Hs 944; HS944
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982).
Part of: TCGA-110-CL cell line panel.
Doubling time: 30 hours (PubMed=25984343).
Omics: Deep exome analysis.
Omics: Deep quantitative proteome analysis.
Omics: Deep RNAseq analysis.
Omics: DNA methylation analysis.
Omics: shRNA library screening.
Omics: SNP array analysis.
Omics: Transcriptome analysis.
Misspelling: Hs-994; In Cosmic 706096 and Cosmic 888839.
Sequence variations Mutation; HGNC; 1787; CDKN2A; Simple; p.His83Tyr (c.247C>T) (p.Ala97Val, c.290C>T); ClinVar=VCV000376307; Zygosity=Homozygous (DepMap).
Mutation; HGNC; 16712; FBXW7; Simple; p.Arg479Gln (c.1436G>A); ClinVar=VCV000376419; Zygosity=Heterozygous (DepMap).
Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (PubMed=10766161; PubMed=15009714; DepMap).
Mutation; HGNC; 9588; PTEN; Simple; p.Lys163fs (c.486_487insA); Zygosity=Heterozygous (DepMap).
Mutation; HGNC; 11730; TERT; Simple; c.242_243CC>TT (-138/-139CC>TT); Zygosity=Unspecified; Note=In promoter (PubMed=31068700).
Mutation; HGNC; 11998; TP53; Simple; p.Lys382Asnfs*40 (c.1146delA); Zygosity=Homozygous (DepMap).
Genome ancestry Source: PubMed=30894373

Origin % genome
African 0
Native American 0
East Asian, North 2.22
East Asian, South 0
South Asian 0
European, North 66.41
European, South 31.37
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 51Y
Category Cancer cell line
Publications
PubMed=6500159; DOI=10.1159/000163283
Gershwin M.E., Lentz D., Owens R.B.
Relationship between karyotype of tissue culture lines and tumorigenicity in nude mice.
Exp. Cell Biol. 52:361-370(1984)

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