Human Chondrocytes: HC cells人软骨细胞 BioVector NTCC质粒载体菌种细胞基因保藏中心
- 价 格：¥99865
- 货 号：Human Chondrocytes HC
- 产 地：北京
- BioVector NTCC典型培养物保藏中心
- 联系人：Dr.Xu, Biovector NTCC Inc.
电话：400-800-2947 工作微信:1843439339 (QQ同号)
邮件：Biovector@163.com
手机：18901268599
地址：北京
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Human Chondrocytes: HC cells人软骨细胞
DESCRIPTIONHuman Chondrocytes (HC) are derived from normal human articular cartilage, where they produce and maintain the extracellular matrix of cartilage, including type II collagen. Used widely in research, the cells are a gold standard control for cellular reprogramming and differentiation. Chondrocytes grown in monolayer culture on a solid surface tend to lose their phenotypic markers, no longer produce Collagen type II and sulfated proteoglycan, and de-differentiate to a fibroblast-like phenotype. In order to regain phenotypic characteristics, de-differentiated chondrocytes should be re-differentiated by encapsulating in alginate beads using the Chondrocyte Differentiation Kit (Cat# 072K).Examples of HC-based research include:Phenotypic characterization and differentiation into osteoclasts. Others employ chondrocytes to describe the molecular biology of cell receptors, signaling cascades, cytokine activation and gene regulation. The cells are implicated in apoptosis, cytotoxicity, and cartilage degradation seen in inflammatory disorders such as rheumatoid-, osteo- and Lyme disease-associated arthritis. By examining the effects of shear stress and mechanotransduction pathways, some hope to develop treatments to thwart erosive joint pathology. Some labs look at monoclonal antibody treatment, or inhibition of erosive matrix metalloproteinase enzymes, directed toward arthritis treatment. The cells also receive attention for potential clinical applications, since they adhere to medical implants and infiltrate scaffolds for cartilage regeneration.Characterization: Positive for aggrecan after differentiation DETAILSTissueNormal healthy human articular cartilageQCNo bacteria, yeast, fungi, mycoplasma, virusBioassayAttach, spread, proliferate in Growth MedCryovial500,000 HC (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSOKitCryovial frozen HC (402-05), Growth Medium (411-500), Subculture Rgnt Kit (090K)ProliferatingShipped in Gr Med, 2nd psg (flasks or plates)DoublingsAt least 10
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
DESCRIPTIONHuman Chondrocytes (HC) are derived from normal human articular cartilage, where they produce and maintain the extracellular matrix of cartilage, including type II collagen. Used widely in research, the cells are a gold standard control for cellular reprogramming and differentiation. Chondrocytes grown in monolayer culture on a solid surface tend to lose their phenotypic markers, no longer produce Collagen type II and sulfated proteoglycan, and de-differentiate to a fibroblast-like phenotype. In order to regain phenotypic characteristics, de-differentiated chondrocytes should be re-differentiated by encapsulating in alginate beads using the Chondrocyte Differentiation Kit (Cat# 072K).Examples of HC-based research include:Phenotypic characterization and differentiation into osteoclasts. Others employ chondrocytes to describe the molecular biology of cell receptors, signaling cascades, cytokine activation and gene regulation. The cells are implicated in apoptosis, cytotoxicity, and cartilage degradation seen in inflammatory disorders such as rheumatoid-, osteo- and Lyme disease-associated arthritis. By examining the effects of shear stress and mechanotransduction pathways, some hope to develop treatments to thwart erosive joint pathology. Some labs look at monoclonal antibody treatment, or inhibition of erosive matrix metalloproteinase enzymes, directed toward arthritis treatment. The cells also receive attention for potential clinical applications, since they adhere to medical implants and infiltrate scaffolds for cartilage regeneration.Characterization: Positive for aggrecan after differentiation DETAILSTissueNormal healthy human articular cartilageQCNo bacteria, yeast, fungi, mycoplasma, virusBioassayAttach, spread, proliferate in Growth MedCryovial500,000 HC (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSOKitCryovial frozen HC (402-05), Growth Medium (411-500), Subculture Rgnt Kit (090K)ProliferatingShipped in Gr Med, 2nd psg (flasks or plates)DoublingsAt least 10
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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