B128 7.13 Helicobacter pylori strain幽门螺杆菌菌株 BioVector NTCC质粒载体菌种细胞基因保藏中心

B128 7.13 Helicobacter pylori strain幽门螺杆菌菌株

Helicobacter pylori represents an interesting model of bacterial pathogenesis given that most infections are asymptomatic, while a minority of infections cause severe gastric disease. H pylori strain B128 7.13 is used extensively to understand H pylori pathophysiology. Due to extensive restriction-modification systems, the fact that only some H pylori strains are naturally transformable, the inability of common plasmid and transposon vectors to replicate in this bacterium, as well as the limited number of antibiotic cassettes that are functional in H pylori, there are relatively few genetic tools for the mutagenesis of this bacterium.

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