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ACH-2 cell line (HIV感染的人T细胞)
Cell line name ACH-2Synonyms ACH2 Comments Derived from sampling site: Peripheral blood.Sequence variations Gene fusion; HGNC; 13222; BCL11B + HGNC; 2488; NKX2-5; Name(s)=NKX2.5-BCL11B (from parent cell line).Mutation; HGNC; 16712; FBXW7; Simple; p.Arg465Cys (c.1393C>T); ClinVar=VCV000376414; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 3765; FLT3; Simple; p.Ala627Thr (c.1879G>A); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1593_Arg1594insProArgLeuProHisAsnSerSerPheHisPheLeu (c.4780_4781ins36); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 7881; NOTCH1; Simple; p.Pro2412Thr (c.7234C>A); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Parent: CVCL_6244 (CEM A3.01)Sex of cell FemaleAge at sampling 3Y11MCategory Cancer cell linePublications PubMed=2463307Clouse K.A., Powell D., Washington I., Poli G., Strebel K., Farrar W.L., Barstad P., Kovacs J., Fauci A.S., Folks T.M.Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone.J. Immunol. 142:431-438(1989)
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
Cell line name ACH-2Synonyms ACH2 Comments Derived from sampling site: Peripheral blood.Sequence variations Gene fusion; HGNC; 13222; BCL11B + HGNC; 2488; NKX2-5; Name(s)=NKX2.5-BCL11B (from parent cell line).Mutation; HGNC; 16712; FBXW7; Simple; p.Arg465Cys (c.1393C>T); ClinVar=VCV000376414; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 3765; FLT3; Simple; p.Ala627Thr (c.1879G>A); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 7881; NOTCH1; Simple; p.Leu1593_Arg1594insProArgLeuProHisAsnSerSerPheHisPheLeu (c.4780_4781ins36); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 7881; NOTCH1; Simple; p.Pro2412Thr (c.7234C>A); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Parent: CVCL_6244 (CEM A3.01)Sex of cell FemaleAge at sampling 3Y11MCategory Cancer cell linePublications PubMed=2463307Clouse K.A., Powell D., Washington I., Poli G., Strebel K., Farrar W.L., Barstad P., Kovacs J., Fauci A.S., Folks T.M.Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone.J. Immunol. 142:431-438(1989)
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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