BON-1 cell line人胰腺神经内分泌瘤细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心
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BON-1 cell line人胰腺神经内分泌瘤细胞株
Cell line name BON-1Synonyms Bon-1; BON1; BONComments Doubling time: 1.5 +- 0.4 days (PubMed=29330294); 46 +- 0.72 hours (PubMed=32884006).Omics: Array-based CGH.Omics: Deep exome analysis.Omics: Deep quantitative proteome analysis.Omics: SNP array analysis.Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=29444910).Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (PubMed=29444910).Mutation; HGNC; 583; APC; Simple; p.Glu1317Gln (c.3949G>C); ClinVar=VCV000000829; Zygosity=Heterozygous (PubMed=29444910).Mutation; HGNC; 1101; BRCA2; Simple; p.Cys1960Tyr (c.5879G>A); ClinVar=VCV000038003; Zygosity=Heterozygous (PubMed=29444910).Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (PubMed=29444910).Mutation; HGNC; 11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Homozygous (PubMed=29444910).Disease Pancreatic serotonin-producing neuroendocrine tumor (NCIt: C4446)Serotonin-producing neuroendocrine tumor of pancreas (ORDO: Orphanet_506090)Derived from metastatic site: Lymph node.Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Children:CVCL_WV97 (BON1 RR1 ) CVCL_WV98 (BON1 RR2 ) CVCL_A1AU (BON1-MEN1-KO )Sex of cell MaleAge at sampling 28YCategory Cancer cell lineSTR profile Source(s): PubMed=29444910Markers:Amelogenin X,YCSF1PO 10,11D5S818 9,12D7S820 9D13S317 11,12D16S539 10,11D21S11 28,33.2TH01 8TPOX 9vWA 18,19PubMed=1712329; DOI=10.5555/uri:pii:0016508591900045Evers B.M., Townsend C.M. Jr., Upp J.R. Jr., Allen E., Hurlbut S.C., Kim S.W., Rajaraman S., Singh P., Reubi J.C., Thompson J.C.Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth.Gastroenterology 101:303-311(1991)
Supplier来源:BioVector NTCC Inc.
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Cell line name BON-1Synonyms Bon-1; BON1; BONComments Doubling time: 1.5 +- 0.4 days (PubMed=29330294); 46 +- 0.72 hours (PubMed=32884006).Omics: Array-based CGH.Omics: Deep exome analysis.Omics: Deep quantitative proteome analysis.Omics: SNP array analysis.Sequence variations Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (PubMed=29444910).Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (PubMed=29444910).Mutation; HGNC; 583; APC; Simple; p.Glu1317Gln (c.3949G>C); ClinVar=VCV000000829; Zygosity=Heterozygous (PubMed=29444910).Mutation; HGNC; 1101; BRCA2; Simple; p.Cys1960Tyr (c.5879G>A); ClinVar=VCV000038003; Zygosity=Heterozygous (PubMed=29444910).Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Arg (c.182A>G); ClinVar=VCV000013900; Zygosity=Homozygous (PubMed=29444910).Mutation; HGNC; 11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Homozygous (PubMed=29444910).Disease Pancreatic serotonin-producing neuroendocrine tumor (NCIt: C4446)Serotonin-producing neuroendocrine tumor of pancreas (ORDO: Orphanet_506090)Derived from metastatic site: Lymph node.Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Children:CVCL_WV97 (BON1 RR1 ) CVCL_WV98 (BON1 RR2 ) CVCL_A1AU (BON1-MEN1-KO )Sex of cell MaleAge at sampling 28YCategory Cancer cell lineSTR profile Source(s): PubMed=29444910Markers:Amelogenin X,YCSF1PO 10,11D5S818 9,12D7S820 9D13S317 11,12D16S539 10,11D21S11 28,33.2TH01 8TPOX 9vWA 18,19PubMed=1712329; DOI=10.5555/uri:pii:0016508591900045Evers B.M., Townsend C.M. Jr., Upp J.R. Jr., Allen E., Hurlbut S.C., Kim S.W., Rajaraman S., Singh P., Reubi J.C., Thompson J.C.Establishment and characterization of a human carcinoid in nude mice and effect of various agents on tumor growth.Gastroenterology 101:303-311(1991)
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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