MZ-CRC-1 cell line人遗传性甲状腺髓样癌细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

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货　　号：MZ-CRC-1
产　　地：北京

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MZ-CRC-1 cell line人遗传性甲状腺髓样癌细胞株

Cell line name MZ-CRC-1
Synonyms MZCRC1

Comments Doubling time: 12-16 days (CelloPub=CLPUB00385).
Omics: Transcriptome analysis.

Sequence variations
Mutation; HGNC; 4778; H3-4; Simple; p.Arg3Ter (c.7C>T); Zygosity=Heterozygous (PubMed=30737244).
Mutation; HGNC; 6913; MAX; Simple; c.295+1G>A; ClinVar=VCV000186993; Zygosity=Homozygous; Note=Splice donor mutation (PubMed=30737244).
Mutation; HGNC; 30064; PBRM1; Simple; p.Arg534Ter (c.1600C>T); Zygosity=Homozygous (PubMed=30737244).
Mutation; HGNC; 9967; RET; Simple; p.Met918Thr (c.2753T>C); ClinVar=VCV000013919; Zygosity=Heterozygous (PubMed=19897677; PubMed=30737244).

Disease Hereditary thyroid gland medullary carcinoma (NCIt: C46099)
Familial medullary thyroid carcinoma (ORDO: Orphanet_99361)
Derived from metastatic site: Pleural effusion.

Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 43Y
Category Cancer cell line

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