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MR49F cell line人前列腺癌细胞株
Cell line name MR49FSynonyms MR49-F; ENZR 49F; 49FENZRAccession CVCL_RW53Resource Identification Initiative To cite this cell line use: MR49F (RRID:CVCL_RW53)Comments Population: Caucasian.Selected for resistance to: ChEBI; CHEBI:68534; Enzalutamide (Xtandi; MDV-3100).Sequence variations Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).Disease Prostate carcinoma (NCIt: C4863)Derived from metastatic site: Left supraclavicular lymph node.Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Parent: CVCL_0395 (LNCaP)Sex of cell MaleAge at sampling 50YCategory Cancer cell line
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
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Cell line name MR49FSynonyms MR49-F; ENZR 49F; 49FENZRAccession CVCL_RW53Resource Identification Initiative To cite this cell line use: MR49F (RRID:CVCL_RW53)Comments Population: Caucasian.Selected for resistance to: ChEBI; CHEBI:68534; Enzalutamide (Xtandi; MDV-3100).Sequence variations Mutation; HGNC; 644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).Mutation; HGNC; 7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).Mutation; HGNC; 9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).Disease Prostate carcinoma (NCIt: C4863)Derived from metastatic site: Left supraclavicular lymph node.Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)Hierarchy Parent: CVCL_0395 (LNCaP)Sex of cell MaleAge at sampling 50YCategory Cancer cell line
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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