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pcDNA3.1-Snail-EGFP基因表达质粒载体 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥39865
  • 货  号:pcDNA3.1-Snail-EGFP
  • 产  地:北京
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pcDNA3.1-Snail-EGFP基因表达质粒载体

RefSeq NM_003068.5
RefSeq Size 2101 bp
RefSeq ORF 807 bp
Locus ID 6591
Domains zf-C2H2
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Adherens junction
Gene Summary This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.

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