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MDA231-LM2-4175 cell line人乳腺腺癌细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥59865
  • 货  号:MDA231-LM2-4175
  • 产  地:北京
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MDA231-LM2-4175 cell line人乳腺腺癌细胞株

Cell line name MDA231-LM2-4175
Synonyms MDA231-LM2; MDA 231-LM2-4175; MDA-MB-231 #4175; LM2-4175; 4175
Accession CVCL_5998
Resource Identification Initiative To cite this cell line use: MDA231-LM2-4175 (RRID:CVCL_5998)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Population: Caucasian.
Characteristics: Established from MDA231-TGL cell line after 3 passage in nude mice.
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transfected with: UniProtKB; P08659; Firefly luciferase.
Transfected with: UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Omics: Proteome analysis by 2D-DE.
Miscellaneous: STR profile from MSKCC antibody and bioresource core facility.
Sequence variations
Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; 1097; BRAF; Simple; p.Gly464Val (c.1391G>T); ClinVar=VCV000040364; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 6407; KRAS; Simple; p.Gly13Asp (c.38G>A); ClinVar=VCV000012580; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Homozygous (from parent cell line).
Disease Breast adenocarcinoma (NCIt: C5214)
Derived from metastatic site: Pleural effusion.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VR35 (MDA231-TGL)
Sex of cell Female
Age at sampling 51Y
Category Cancer cell line

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