Neisseria meningitidis 5-99 strain脑膜炎双球菌菌株 BioVector NTCC质粒载体菌种细胞基因保藏中心

Neisseria meningitidis 5-99 strain脑膜炎双球菌菌株

Neisseria meningitidis strain NZ98/254 is a relatively low expresser of FHbp identification (ID) 14 (subfamily B) (7) and was used in flow cytometric studies as a control to measure FHbp expression. The remaining control strains were each mismatched for three of the four antigens in MenB-4C known to elicit serum bactericidal activity. Thus, the serum bactericidal activity elicited by the MenB-4C vaccine against N. meningitidis strain H44/76 is specific for antibodies to FHbp, N. meningitidis strain 5/99 is specific for antibodies to NadA, and N. meningitidis strain SK016 is specific for antibodies to PorA P1.4. In past studies, finding a control strain that is specific for anti-NHba bactericidal activity has been problematic

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