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J-Lat 10.6 cell line儿童急性T淋巴细胞白血病细胞株 BioVector NTCC质粒载体菌种细胞基因保藏中心

  • 价  格:¥98965
  • 货  号:J-Lat 10.6
  • 产  地:北京
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J-Lat 10.6 cell line儿童急性T淋巴细胞白血病细胞株

Cell line name J-Lat 10.6 Synonyms J-Lat clone 10.6; J-Lat full length clone 10.6 Accession NTCC®_8281 Resource Identification Initiative To cite this cell line use: J-Lat 10.6 (NTCC®_8281) Comments Population: Caucasian. Virology: Latently infected with HIV-1 strain R7/E-/GFP. The integrated HIV-1 genome is located in SEC16A 2nd intron (PubMed=28086908; PubMed=32354973). Transfected with: UniProtKB; P42212; GFP. Derived from sampling site: Peripheral blood. Cell type=T-cell. Sequence variations Mutation; HGNC; 959; BAX; Simple; p.Glu41Argfs*19 (c.121delG); ClinVar=VCV000009512; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 959; BAX; Simple; p.Glu41Glyfs*33 (c.121dupG); ClinVar=VCV000009511; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 16712; FBXW7; Simple; p.Arg505Cys (c.1513C>T); ClinVar=VCV000069961; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 6079; INPP5D; Simple; p.Gln345Ter (c.1033C>T); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 6079; INPP5D; Simple; c.1097+1065_1097+1112del47; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; 7325; MSH2; Simple; p.Arg711Ter (c.2131C>T); ClinVar=VCV000090903; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 7329; MSH6; Simple; p.Phe1088Serfs*2 (c.3261delC); ClinVar=VCV000089363; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; 11998; TP53; Simple; p.Arg196Ter (c.586C>T); ClinVar=VCV000043589; Zygosity=Heterozygous (from parent cell line). Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861) Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606) Hierarchy Parent: NTCC®_0065 (Jurkat) Sex of cell Male Age at sampling 14Y Category Cancer cell line

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