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Kif7 gene基因表达质粒敲除编辑载体
BioVector® Human kinesin family member 7 (KIF7)RefSeq NM_198525.1, NP_940927.1RefSeq Size 3121 bpRefSeq ORF 4032 bpLocus ID 374654Protein Families Druggable GenomeMW 94.8 kDaGene Summary This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
BioVector® Human kinesin family member 7 (KIF7)RefSeq NM_198525.1, NP_940927.1RefSeq Size 3121 bpRefSeq ORF 4032 bpLocus ID 374654Protein Families Druggable GenomeMW 94.8 kDaGene Summary This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Supplier来源:BioVector NTCC Inc.
TEL电话:400-800-2947
Website网址: http://www.biovector.net
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