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[Designation名称] NTCC® Synonyms: MGH121 Res # 1 Cell Line细胞株
BioVector NTCC Inc.Synonyms细胞别名: Cell Line Name: MGH121 Res#1Comments: Selected for resistance to: ChEBI; CHEBI_61400; WZ4002 (N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide).NTCC® Accession Number: CVCL_E4DNReferences identifiers: PubMed=25964297;Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous (PubMed=25964297).Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Cys797Ser (c.2389T>A); ClinVar=VCV000376342; Zygosity=Heterozygous; Note=Responsible for resistance to WZ4002. Located in the same allele as the p.Thr790Met mutation (PubMed=25964297).Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex19del; Zygosity=Unspecified (from parent cell line).Comments: Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.Diseases: C2926; Lung non-small cell carcinomaSpecies of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)Hierarchy: CVCL_DH49 ! MGH121Sex of cell: Sex unspecifiedAge of donor at sampling: Age unspecifiedCategory: Cancer cell lineDate (entry history): Created: 19-12-24; Last updated: 10-04-25; Version: 2
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC®-NTCC® Accession Number: CVCL_E4DN
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Hierarchy]
培养方法:
Medium培养基:NTCC® Synonyms: MGH121 Res # 1 Complete Medium
Growth properties形态:贴壁/悬浮:
Culture Condition培养条件:Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址:www.biovector.net
BioVector NTCC Inc.Synonyms细胞别名: Cell Line Name: MGH121 Res#1Comments: Selected for resistance to: ChEBI; CHEBI_61400; WZ4002 (N-(3-(5-chloro-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)acrylamide).NTCC® Accession Number: CVCL_E4DNReferences identifiers: PubMed=25964297;Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous (PubMed=25964297).Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Cys797Ser (c.2389T>A); ClinVar=VCV000376342; Zygosity=Heterozygous; Note=Responsible for resistance to WZ4002. Located in the same allele as the p.Thr790Met mutation (PubMed=25964297).Comments: Sequence variation: Mutation; HGNC; HGNC:3236; EGFR; Unexplicit; Ex19del; Zygosity=Unspecified (from parent cell line).Comments: Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.Diseases: C2926; Lung non-small cell carcinomaSpecies of origin: NCBI_TaxID=9606; ! Homo sapiens (Human)Hierarchy: CVCL_DH49 ! MGH121Sex of cell: Sex unspecifiedAge of donor at sampling: Age unspecifiedCategory: Cancer cell lineDate (entry history): Created: 19-12-24; Last updated: 10-04-25; Version: 2
[Organism物种来源]
[Disease疾病种类]
[Accession编号] NTCC®-NTCC® Accession Number: CVCL_E4DN
[Comments描述]
[Reference参考文献]
[Category分类]
[Date保藏时间]
[Hierarchy]
培养方法:
Medium培养基:NTCC® Synonyms: MGH121 Res # 1 Complete Medium
Growth properties形态:贴壁/悬浮:
Culture Condition培养条件:Temperature温度: 37°C.Atmosphere: 95% Air, 5% CO2
Supplier生产厂家: BioVector NTCC质粒载体菌种细胞蛋白抗体基因保藏中心
Website网址:www.biovector.net
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